There are several tools that can aid in the debugging of your OpenGL program.
Debug Output is an OpenGL feature that makes error checking from functions easier. It is a core feature of GL 4.3, and available through extensions for older versions.
Most drivers expose this functionality only on debug contexts: context should be created with CONTEXT_DEBUG_BIT set..
Home page: https://renderdoc.org/
Description: RenderDoc is a stand-alone graphics debugging tool, released under the MIT License, that supports OpenGL 3.2+ (Core Profile only) development on Windows and Linux. Besides OpenGL, RenderDoc can also be used to debug Vulkan and several other graphics APIs. Online documentation is available at https://renderdoc.org/docs/index.html.
Home page: https://www.opengl.org/sdk/tools/BuGLe/
Description: BuGLe is a free (as in freedom) software released under the GPLv2. It is a toolkit for debugging and profiling OpenGL applications running on UNIX-like systems. It consists of two parts: a collection of filter-sets that observe and sometimes modify calls to the OpenGL API, and a graphical debugger (gldb-gui) that helps in setting breakpoints, capturing errors, and examining state (including shader code, buffers and a visual feedback of the textures, the color buffers and depth buffer).
Note: It was officially announced on November 23 2014 that BuGLe is no longer being developed. 
AMD CodeXL (previously: gRemedy, gDEBugger)
Description: gDebugger is a commercial application that hooks to your application and displays info in text and graphical form in its own window. It can also show GPU utilization. You can use it to find out where the bottleneck is in your app. There are Windows and Linux versions.
It also supports GL_GREMEDY_string_marker http://www.opengl.org/registry/specs/GREMEDY/string_marker.txt
GL_GREMEDY_string_marker is for leaving markers in your source code, so that it becomes easier for you to locate where the problem is.
Description: APITrace is another free (as in freedom) software. It is a toolkit for debugging and profiling OpenGL and DirectX applications running on Linux or Windows. You first run your program to generate a "trace file", and this file can then be replayed or explored using the tools provided.
Download from https://github.com/dtrebilco/glintercept
GLIntercept is a free open sourced program intended for Windows platforms. After installing, a folder (C:\Program Files\GLIntercept*_* where the asterisks are the version numbers) will have been created. This folder holds several sample configuration files of interest which can be used to configure GLIntercept: gliConfig.ini, gliConfig_AuthorStd.ini, gliConfig_ExtOverride.ini, etc. In addition, this folder holds a version of the
OpenGL32.dll file which acts an intermediary between your system's OpenGL implementation and GLIntercept. To utilize this functionality, copy the DLL and a customized copy of the gliConfig.ini file to your application's target folder (usually where the .EXE resides) and run your application. All invoked OpenGL function calls will route through the DLL, allowing GLIntercept to detect:
- Function calls before context creation
- Resource leaks
Once you close your app, GLI dumps the above info into gliLog.txt.
You may configure GLI to output a XML log file (upon pressing [Ctrl]+[Shift]+[f]) showing all of the OpenGL functions called, problems and used shaders and textures. GLI will make a folder where your EXE is and places the XML files and all related files like screen captures and textures.
In gliConfig.ini, check out section "LogPerFrame".
Cons: The program is intended for applications that have a single GL context. Windows Only. It is compatible with OpenGL 3.x and above, but it will not provide the best form of logging for some of the more recent APIs and extensions.
Description: GLSL-Debugger is similar in concept to gDebugger. It works transparently just like gDebugger, and it can debug the shaders line by line. It is also free.
Linux and Windows.
The source code has been opened in 2013 and actively developing Open Source fork is now available: http://glsl-debugger.github.io/. This is a fork of the original glslDevil project.
Vogl is a free (as in freedom) software released under the MIT License by RAD Game Tools and Valve Software. It is an OpenGL capture / playback debugger running on Linux and Windows. There is also a Mac OS port which is not yet functional (as of Jan 10 2015). 
AMD GPU PerfStudio
http://gpuopen.com/archive/gpu-perfstudio/ Supports Windows and Linux, can be used to analyze frames, see textures, buffers, shaders, etc. Also works on non-AMD hardware.
The Visual Studio Edition that allows visual debugging and profiling of OpenGL / CUDA / D3D (and more) programs.